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pentobarbital will reduce the level or influence of vinorelbine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.pentobarbital will minimize the level or result of abemaciclib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of abemaciclib with